The Organizing Committee of the 4th. Mini Symposium: Implications on Survival and Death Mechanisms for the Interactions of Pathogenic Protozoa with their Hosts welcomes all participants to our one-day meeting in São Paulo. We would like to specially thank all of the invited speakers for their valuable contributions, as well as the participants. This year, we organized the meeting in four Round Tables approaching different topics on the biology of pathogenic protists. We would like to acknowledge also the financial support of the following funding agencies and Institutions: FAPESP, University of São Paulo and Global Challenges Research Funds. We wish all the participants an interesting and productive meeting.
Event location: Departamento de Parasitologia
Instituto de Ciências Biomédicas – USP
Edifício Biomédicas II – Auditório Principal
Event date: 8. Nov. 2019
Welcome to the participants
9:00 – 11:00
Round Table 1: DNA, RNA and proteins in trypanosomatids
Prof. Christine Clayton – University of Heidelberg, Center for Molecular Biology [ZMBH] Heidelberg – Germany
Title: Mechanisms of selective translation stimulation and suppression by the multiple eIF4E isoforms of Trypanosoma brucei.
Prof. Julia Pinheiro Chagas da Cunha – Special Cell Cycle Laboratory, Butantan Institute – BR
Title: Epigenenomics and chromatin proteomics of Trypanosoma cruzi.
Prof. Jessica Kissinger – University of Georgia at Athens, Athens – USA
Title: The EuPathDB.org Family of Databases for Host- Pathogen Research.
11:00 – 13:00
Poster session and interactive brunch
13:00 – 15:00
Round Table 2: New advances in chemoterapy and drug discovery in apicomplexa
Prof. Sebàstièn Besteiro – Université de Montpellier, Montpellier – France
Title: The many sides of Toxoplasma autophagy machinery.
Prof. Gustavo Arrizabalaga – Indiana University, Indiana University School of Medicine, Indiana – USA
Title: The phosphatases of Toxoplasma gondii.
Prof. Paul Horrocks – Keele University, Keele – UK
Title: Cell death in the human malaria parasite: exploring autophagy as a drug target and early events following drug perturbation.
15:00 – 15:30
Interactive coffee break
15:30 – 17:30
Round Table 3: Translational parasitology: from experimental models to patients
Prof. Igor Correa de Almeida – University of Texas, El Paso – USA
Title: Trypanosoma cruzi α-Gal-terminating neoglycoproteins as biomarkers for early assessment of chemotherapeutic outcomes in Chagas disease.
Prof. Michael Lewis – London School of Hygiene and Tropical Medicine, London – UK
Title: Fatal progression of experimental visceral leishmaniasis is associated with intestinal parasitism and secondary infection by commensal bacteria, and is delayed by antibiotic prophylaxis.
Prof. Helen Price – Keele University, School of Life Sciences, Keele – UK
Title: Introducing ECLIPSE: a new intervention programme to improve patient journey and reduce stigma for people with cutaneous leishmaniasis.